In each Report Run, you can find the tab Exchange Rates, which will contain all the currencies present in each sales report uploaded in the run.
You need to add the exchange rate of each currency that translates to the currency on which your account is based.
For example, if your account is set in euros and you've uploaded sales reports containing royalties in US dollars, the Exchange Rates tab will display the currency US Dollars. You will need to add a value (rate) corresponding to the US Dollars to Euros.